Russia’s military losses in Ukraine have totaled approximately 22,800 troops.

A Ukrainian Air Assault Forces unit annihilated a modified Russian BTR-80 armored personnel carrier and its crew.

The Ukrainian Air Assault Forces’ press service released a video in this regard.

“A unit of Russian occupiers destroyed and liquidated on Ukrainian soil certainly inspires admiration and pride in our paratroopers, because we did not allow Putin’s army to advance deep into our territory, preventing them from killing our people.

What is more interesting for military armored vehicle experts is that Ukrainian paratroopers destroyed an upgraded and modified version of the Russian armored personnel carrier BTR-80 “According to the statement.

The video, in particular, shows that the destroyed Russian armored vehicle was outfitted with a new sight and searchlight.

According to the statement, the invaders and their armored vehicle were destroyed by soldiers from Ukraine’s Armed Forces’ 80th Separate Air Assault Brigade.

Russia’s military losses in Ukraine have totaled approximately 22,800 troops since the start of the full-fledged Russian invasion.

Homepage

Hypocobalaminemia or Vitamin B12 deficiency, as the name indicates.

Introduction

Hypocobalaminemia or Vitamin B12 deficiency, as the name indicates, it is a condition characterized by a lack of the water soluble vitamin known as B12. A deficiency of this vitamin, which is vital for physical processes, increases the risk of heart attack and can damage the nerve cells apart from giving rise to a host of other problems.

What is vitamin B12?

Also referred to as Cobalamin, it is an important vitamin that is necessary for a number of vital functions of the body. Along with the B vitamin folate, it helps create the genetic material of the human body. It helps maintain the levels of the amino acid known as homocysteine – which is supposed to reduce the risk of heart attacks. It is also important for the manufacture of red blood cells or RBCs which transport oxygen to various tissues of the body through blood.

History

Vitamin B12 was discovered in 1926 by Georg Richard Minot and William Parry Murphy, who found that eating large quantities of liver restored red blood cells in patients with pernicious anemia (the inability to make enough red blood cells). In 1934, both scientists, as well as George Whipple, won a Nobel Prize for their work in treatment of pernicious anemia. Vitamin B12 wasn’t officially isolated until 1948.

Epidemiology

The prevalence of vitamin B-12 deficiency is difficult to ascertain because of diverse etiologies and different assays (i.e., radio assay or chemiluminescence). Affected individuals may number 300,000 to 3 million in the United States.

PA prevalence may be higher in white people and lower in Hispanic and black people. No known relationship exists between neurologic symptoms and race. Studies in Africa and the United States have shown higher vitamin B-12 and transcobalamin II levels in black than in white individuals. Additionally, blacks have lower HC levels and metabolize it more efficiently than whites.

In Europe and Africa, the prevalence of PA is higher in elderly women than men (1.5:1), while in the United States no differences exist. Men have higher HC levels at all ages. Pregnancy and estrogen replacement in postmenopausal women lower HC levels.

PA occurs in people of all ages, but it is more common in people older than 40-70 years and, in particular, in people older than 65 years. In white people, the mean age of onset is 60; in black people, the mean age is 50 years. Congenital PA manifests in children aged 9 months to 10 years; the mean age is 2 years.

Common causes of vitamin B12 deficiency

Impaired gastric absorption

Pernicious anaemia

Gastrectomy—partial or total

Zollinger-Ellison syndrome

Impaired intestinal absorption

Ileal resection or disease—for example, Crohn’s inflammatory bowel disease and tuberculous ileitis

Blind loop syndrome

Luminal disturbances: chronic pancreatic disease and gastrinoma

Parasites: giardiasis, bacterial overgrowth, and fish tapeworm

Pancreatic insufficiency

Decreased intake

Malnutrition

Reduced intake of animal products

Strict vegan diet

Congenital/inherited

Intrinsic factor receptor deficiency/defect—ImerslundGräsback syndrome

Congenital deficiency of intrinsic factor—“juvenile” pernicious anaemia

Cobalamin mutation (C-G-1 gene)

Transcobalamin deficiency

Increased requirements

  • Haemolysis
  • HIV

Drugs

Alcohol

Nitrous oxide

Proton pump inhibitors

H2 receptor antagonists

Metformin

Colchicine

Slow K (potassium chloride) preparations

Cholestyramine

Risk factors of Hypocobalaminemia

A number of factors can affect your body’s vitamin stores. In general, your risk of vitamin deficiency is increased if:

Your diet contains little to no natural vitamin food sources, such as meat, dairy, fruits and vegetables. Vegetarians who don’t eat dairy products and vegans, who don’t eat any foods from animals, may fall into this category. Consistently overcooking your food also can cause vitamin deficiency.

You’re pregnant, and you aren’t taking a multivitamin. Folic acid supplements are especially important during pregnancy.

You have intestinal problems or other medical conditions that interfere with absorption of vitamins. Abnormal bacterial growth in your stomach or surgery to your intestines or stomach can interfere with the absorption of vitamin B-12.

You abuse alcohol. Alcohol interferes with the absorption of folate and vitamin C, as well as other vitamins.

You take certain prescription medications that can block absorption of vitamins. Anti-seizure drugs can block the absorption of folate. Antacids and some drugs used to treat type 2 diabetes may interfere with B-12 absorption.

Some risk factors are unique to specific vitamin deficiencies.

Folate-deficiency anemia risk factors include:

Undergoing hemodialysis for kidney failure. Ask your doctor whether you need supplemental folic acid to prevent a deficiency.

Cancer treatment. Some drugs used to treat cancer can interfere with the metabolism of folate.

Risk factors for Hypocobalaminemia include:

A family history of the disease

Having part or all of your stomach or intestine removed

Autoimmune diseases, including type 1 diabetes

Crohn’s disease

HIV

Some medicines

Strict vegetarian diets

Being an older adult

Signs and symptoms

Hypocobalaminemia should be suspected in the following circumstances and warrants further investigation:

Unexplained anaemia

Unexplained neurological or psychiatric features

Gastrointestinal problems such as sore tongue, anorexia, diarrhoea

Prolonged use of certain medications

The consequences of clinically important decreases in vitamin B12, such as macrocytic anaemia, neuropathy and mental changes, can be profound. Specific signs and symptoms of Hypocobalaminemia include:

Neurologic – difficulty walking, loss of vibratory sense, impaired sense of touch, peripheral neuropathy

Psychiatric – irritability, personality changes, depression, psychosis, mild memory impairment

Cardiovascular – possible increased risk of myocardial infarction and stroke, palpitations

Anorexia, mild weight loss diarrhoea, atrophic glossitis

Urologic – difficulty in urination

Dyspnoea

Vertigo

Tinnitus

Hypocobalaminemia complications

Long-time sufferers of this condition tend to develop PA. PA sufferers have a higher risk of developing stomach cancers. If left without being treated, the disorder can result in acute neuropathies which include

  • Optic neuropathy
  • Encephalopathy
  • Myelopathy

Long-term vitamin B12 deficiency can cause:

Confusion

Dementia

Depression

Loss of balance

Numbness and tingling in your hands and feet

Those deficient in Vitamin B12 may also suffer from a lack of other important nutrients. In such cases, the condition may be complicated by the occurrence of a number of other nutritional disorders.

In some rare cases, patients suffer from side effects arising due to Vitamin B12 supplementation. Very rarely, affected individuals suffer from hypersensitivity which is characterized by problems like:

Itching

Inflammation

Shock

Sometimes, extremely high doses may result in acne problems. Other rare side effects include:

Cardiac arrhythmia

Dizziness

Hot flushes

Nausea

Skin rash

Hypocobalaminemia diagnosis

Doctors usually begin the diagnosis of this syndrome by asking patients about the symptoms that they have been experiencing. This is followed by a physical examination, in which physicians look for the following symptoms:

Paleness or yellowness of skin

Tachycardia, or abnormally fast heart rate

Changes in the eyes

Elevated body temperature

Enlarged spleen (Splenomegaly)

Patients are likely to exhibit even more symptoms. Based on the severity of the disorder, they may also experience pinpricks and loss of temperature sensations. This may be followed by a number of tests, which include:

Blood tests

These exams reveal a deficiency in the level of B12 vitamin in blood. A lack of this component, and the presence of clinical symptoms of the disorder, confirm the diagnosis. Complete Blood Count (CBC) may indicate the presence of anemia.

Schilling test

In this method, a sufferer is administered with B12 in an injected or tablet form to assess whether it is being properly absorbed by the body.

Bone marrow test

In some cases, this exam may be carried out to diagnose the condition by allowing microscopic examination of cells.

Metabolite assessment

If the levels of Vitamin B12 in blood are borderline, blood may be tested for metabolites such as Methylmalonic acid and Homocysteine. This can help either affirm or rule out the diagnosis of B12 deficiency.

Treatment of Hypocobalaminemia

Treatment involves raising your vitamin B12 levels and will vary based on the cause of your deficiency. Your doctor may recommend:

Shots of vitamin B12 (monthly or more often, if needed)

Vitamin B12 supplements, in pill form or as a nasal spray

Treatment of underlying conditions, such as Crohn’s disease, celiac disease, or alcoholism

Dietary changes

Treatment for this condition involves replacing the missing vitamin B12. People who cannot absorb B12 need regular injections.

When injections first are administered, a patient with severe symptoms may receive five to seven during the first week to restore the body’s reserves of this nutrient.

A response usually is seen within 48 to 72 hours, with brisk production of new red blood cells. Once B12 reserves reach normal levels, injections of vitamin B12 will be needed every one to three months to prevent symptoms from returning.

People who cannot absorb vitamin B12 should continue to eat a well-balanced diet that provides other nutrients (folic acid, iron and vitamin C) necessary to produce healthy blood cells.

Sometimes people can take high doses of oral B12 to provide replacement instead of undergoing injections, but a physician should closely supervise this.

In people whose vitamin B12 deficiency is related to overgrowth of intestinal bacteria, treatment with oral antibiotics, such as tetracycline (sold under several brand names), may stop bacterial overgrowth and allow the absorption of vitamin B12 to return to normal.

Vitamin B12 deficiency resulting from inadequate dietary intake is the easiest to treat. The condition can be reversed by taking oral vitamin B12 supplements and adding foods containing B12.

When the anemia is severe and the red blood cell count is extremely low, blood transfusions may be necessary for the first couple of days until the vitamin B12 injections begin working.

Prevention of Hypocobalaminemia

Strict vegetarians are at higher risk of developing B12 deficiency because of low intake of animal-source foods.

Thus, it is necessary to use plant sources of vitamin B12 to prevent vegetarians from developing a deficiency. These include soybeans, mushrooms and B12 fortified foods such as cereals.

Routine monitoring of vitamin B12 levels should be considered in people prescribed regular proton pump inhibitors and metformin.

Higher consumption of the following foods can help a majority of people avoid this condition:

Milk

Eggs

Seafood

Cheese

Poultry

Meat

If you do not consume animal products or suffer from a medical condition that prevents proper absorption of nutrients in your body, you are recommended to eat breakfast cereal containing B12 or have a B12-fortified multivitamin.

The amount of Vitamin B12 needed by a person depends on his or her age and gender. Other factors, such as pregnancy and ailments, are also essential to consider. Women who are in a stage of maternity or are breast-feeding their children, require higher amounts of the vitamin.

If you suspect yourself to be exhibiting the symptoms of Vitamin B12 Deficiency, consult a doctor to get your blood tested for this condition.

If you test positive, seek treatment on an immediate basis to attain quick recovery. The faster you seek treatment, the quicker you can recover from this disorder.

South Korean government arrest two and a serving soldier for spying for North Korea.

Two South Koreans, including a serving army captain, have been arrested on charges of stealing military secrets for a suspected North Korean agent who paid them in cryptocurrency, Seoul police said Friday (Apr 29).

The nuclear-armed yet impoverished North – which is technically at war with the South is known to operate an army of thousands of well-trained hackers who have attacked firms, institutions and researchers in South Korea and elsewhere.

But this is the first case where a South Korean civilian and an active-duty military captain were caught trying to obtain military secrets, at the behest of a North Korean agent, the police said in a statement.

One of them is a 29-year-old army captain who allegedly passed login information for South Korea’s Joint Command & Control System – a crucial military-run internal communications network  to the suspected Pyongyang spy, Seoul authorities said.

The other, a 38-year-old businessman who runs a virtual asset management firm, is accused of giving the army captain a wristwatch with a secret camera to aid in intelligence gathering at the request of the spy.

The businessman is also suspected of purchasing and assembling a USB-like hacking device called “Poison Tap” to access the Joint Command & Control System, Seoul police said.

The two men have been arrested on charges of violating the national security law, an official at the Korean National Police Agency told AFP Friday.

Seoul police said the arrested businessman first met the Pyongyang spy in an online community about cryptocurrency around six years ago, and the trio had communicated only via secure messaging service Telegram.

Both were paid in cryptocurrency, the police said. The army captain received about 48 million won (US$37,789) from the North Korean agent, while the 38-year-old businessman got around $600,000.

We will strictly respond to security criminals in accordance to laws and principles, Seoul’s prosecution office said in a statement.

North and South Korea remain technically at war since the 1950-53 Korean War ended with the signing of an armistice and not a peace treaty.

Besides having deployed hackers against other countries and companies, the North has also been accused of exploiting its cyber capabilities for financial gain as it looks to shore up its sanctions-hit economy.

Earlier this month US authorities said Pyongyang-linked hackers were responsible for a $620 million cryptocurrency heist in March targeting players of the popular Axie Infinity game.

A rapid rise in house prices and lacklustre gains on the local stock market have driven many young South Korean adults to look to cryptocurrencies for quick profits, local media has reported.

Homepage

Moyes said his team did not show enough quality in attack and failed to defend properly at times.

West Ham United will have to raise their game if they are to reach the Europa League final after losing 2-1 at home to Eintracht Frankfurt in the first leg of their semi-final on Thursday, manager David Moyes said.

With both teams vying for their first European final in over 40 years, Frankfurt shocked West Ham with a goal in the first minute before adding a second in the latter half to cancel out Michail Antonio’s strike.

Moyes said his team did not show enough quality in attack and failed to defend properly at times.

We’re trying to get to a final, so we made too many poor decisions, whether that be with our passing, finishing or trying to create a goal there were just too many wrong decisions, Moyes told reporters.

We’re only 2-1 down in a two-legged game so we’ll keep going, but we know we really need to up our levels and our standards if we’re going to get through.

The big risk is that they’re a big counter-attack side which will be a risk to us as well.

West Ham striker Antonio said the team were confident of turning things around in the second leg, which will be played in Frankfurt on May 5.

We’ve been in this situation before with Sevilla, he said, referring to their 2-0 second-leg win over Sevilla in the last-16 after they lost the first leg 1-0.

One thing for us is, no matter where we go, we believe we can beat anybody.

We’re going to go there and try to win.

Homepage

Companies in Taiwan, home to the world’s largest contract chipmaker.

The United States is grateful for Taiwan’s efforts to resolve a global shortage of semiconductors and further improvements can be made to speed up supply chains, the top US diplomat in Taipei said on Friday (Apr 29).

Tightness in semiconductor supplies over the past two years has in some cases caused auto and consumer appliance production lines to shut down, and the United States has repeatedly urged Taiwan, as a major chip producer, to do more.

Sandra Oudkirk, director of the American Institute in Taiwan, told an industry forum the COVID-19 pandemic has both increased demand and “stressed” the world’s trading system.

While Taiwan’s semiconductor companies continue to churn out chips at an increasingly fast pace, logistical challenges have stymied efforts to keep up.

We’ve all learned about the long supply chains stretching from the fab to the showroom.

We have made improvements, but room exists for further progress, she said, in a transcript provided by her office.

Oudkirk pointed to US Department of Commerce data that over the last two years the median chip inventory in the United States has fallen from 40 days to fewer than five.

Companies in Taiwan, home to the world’s largest contract chipmaker TSMC, have said they expect tight supplies to continue this year and probably into 2023 even as they ramp up capacity expansion.

Oudkirk said the United States deeply appreciated the willingness of Taiwan’s firms to deal with the problem.

You stepped up production when the auto industry sent out a call for help; you have worked with educational institutions to ensure that we are preparing the next generation of engineers,” she added.

Washington has been keen to get more Taiwanese companies to follow TSMC’s lead and build plants in the United States. TSMC, a major Apple Inc supplier, started construction last year at a site in Arizona where it plans to spend US$12 billion to build a computer chip factory.

Oudkirk said they would be organising a delegation of Taiwanese semiconductor-related firms to visit Phoenix, Arizona this summer to encourage further investment.

Homepage

Victoria Azarenka said the Wimbledon ban on players from Russia and her country makes no sense.

Belarus’ Victoria Azarenka said the Wimbledon ban on players from Russia and her country makes no sense and the former world number one called on the tennis governing bodies to take action against the decision.

The All England Lawn Tennis Club (AELTC), which hosts the grass court Grand Slam, took the decision in the wake of Russia’s invasion of Ukraine and the stand was swiftly condemned by the men’s and women’s tours.

The ATP and the WTA denounced the AELTC decision as “discriminatory”, with Steve Simon, the women’s tour chief, last week warning of “strong reactions”.

“If you are asking me if I agree with Wimbledon or I see their reasoning after being on a personal call with them, I don’t see their reasoning,” Azarenka, who sits on the WTA players’ council, told reporters in Madrid on Thursday.

“It does not make sense and it does not connect to what they are saying.”

The 32-year-old Azarenka, ranked 17th in the world, won her opening round at the WTA 1000 event in Madrid on Thursday but her fellow Belarusian Aryna Sabalenka’s title defence ended with a 6-2 3-6 6-4 defeat to unseeded American Amanda Anisimova.

Tennis governing bodies have banned Russia and Belarus from international team competitions following the invasion, but individual players from the two countries are allowed to continue competing as neutrals.

The 2022 Wimbledon championships will be the first time that players have been banned on the grounds of nationality since the immediate post-World War Two era, when German and Japanese players were excluded.

“I think there should be a reaction to that, that is all I want to say,” said Azarenka, who won the Australian Open in 2012 and 2013.

I have made my stance very clear on the issue. I will never, ever support war.

I will never support violence. I will never find any justifications for that. That is all I can say right now.

Homepage

Leicester in a 1-1 draw with AS Roma.

Leicester City’s performance in Thursday’s 1-1 draw with AS Roma in the first leg of the Europa Conference League semi-final will boost their confidence ahead of next week’s reverse fixture, manager Brendan Rodgers said.

Roma captain Lorenzo Pellegrini put his team ahead in the 15th minute before Gianluca Mancini scored an own goal in the 67th minute, sending in a cross from Leicester’s Harvey Barnes after coming under pressure from Ademola Lookman.

Rodgers said Leicester showed “courage” against Jose Mourinho’s experienced Roma at the King Power Stadium. The teams will meet in Italy for the second leg on May 5.

Our movement and mobility in the game was really good and we arrived into the final third in some really good positions, Rodgers told LCFC TV after the match.

Even though we were behind in the game, we weren’t giving away so much. We were aware, on the counter-attack, they might look to break away.

It was the reaction we needed from the team and I thought that reaction was very good.

Overall, I’m really pleased with the performance and it gives us great confidence now going into the second leg.

Mourinho said Roma gave away the ball too much after the first half and did not capitalise on some chances to counter-attack.

When we started to lose the ball and let the intensity drop, our defensive line dropped a bit and the game became harder for us in the second half, Mourinho told Roma’s website.

But, nevertheless, I am sure that before the game every Roma fan would have happily taken this result because it means everything will be decided at the Olimpico.

I am not smiling though because I know that even with 70,000 fans at the stadium it is going to be a difficult game.

Homepage

Woman charged for aiding love scammers in China.

A 64-year-old woman was charged in court on Thursday (Apr 28) with cheating two banks into opening accounts that were used in Internet love scams.

Yvonne Cecilia de Silva is accused of conspiring with an “Edmond Chin” and a “Chris” to cheat the Industrial and Commercial Bank of China (ICBC) and the Oversea-Chinese Banking Corporation (OCBC) respectively, according to charge sheets.

She was also charged with giving these people the online banking login credentials and an ATM card.

The bank accounts were used by criminals to launder proceeds of crime derived from three reported cases of Internet love scams, said the police.

The victims met the scammers on Facebook and Instagram, and over time transferred a total of S$121,000 at the request of the scammers.

Some money was transferred purportedly to help ease cashflow problems. Money was also transferred on the pretext of paying for fees needed to release parcels sent by their online lovers, said the police.

Investigations revealed that the 64-year-old woman befriended the unknown people on Facebook in 2019. They asked for help to receive funds in Singapore for their businesses.

The woman allegedly cheated two banks into opening two bank accounts in her name, by deceiving them into believing that she was going to use these accounts.

She allegedly mailed a bank ATM card to an address in Malaysia and provided the online banking login credentials to the person.

She is also accused of accepting S$6,000 into her MayBank account for the purpose of transferring the proceeds to another party.

Anyone found guilty of conspiring to cheat a bank into opening a bank account can be jailed for up to three years, fined, or both.

For abetting others to secure unauthorised access to a bank’s computer system, a first-time offender can be fined up to S$5,000, jailed for up to two years, or both.

Those convicted of carrying on the business of providing a payment service in Singapore without licence can be fined up to S$125,000, jailed for up to three years, or both.

The police take a serious stance against anyone involved in facilitating money laundering, and perpetrators will be dealt with in accordance with the law, the police said.

To avoid becoming involved in money laundering activities, members of the public should always reject requests to share the use of their banking facilities to receive and transfer funds, as well as guard against disclosing their Singpass login details which can be misused for many transactions.

Homepage

US warned us but we didn’t listen says Babajide Otitoju.

Babajide Kolade Otitoju, an investigative journalist and historian was asked to react to the alarm raised by DSS recently over the plot to bomb worship centers and other places.

In his reaction Babajide noted that America has warned us that the terrorists will move to the north west but we dismissed it and now it is happening as predicted. Read Babajide’s reaction below.

Now they bombed people at a beer parlour and ISWAP has come out to say that they did it, remember when the Americans warned that these Jihadist elements are going to the north west and a lot of us dismissed it as we usually do.

Today even the ministry of Defence has come out to say Boko Haram and bandits are coming together to plan operations in the north west, but we were warned, the Americans had warned us not less than three to four years ago that these guys were making plans to go to the north west.

Today they are not only in the north west, they are in Niger state, in the Shiroro area, the governor even mentioned communities that they have taken over.

If they can be bombing beer parlour, if they can go to beer parlours to slaughter people like ram, the way they did in Gaidam, how are we sure that they can’t resume attacking mosque and churches, because the truth is that they have attacked mosques in the past so it is not only churches they attack.

They are looking for who to kill, they don’t have a religion, they fool you because they have Muslim names , but it doesn’t make them Muslims, it is your way of life that shows whether you are a Muslim or Christian.

The kind of security measures we put in place in those days are no longer there, routine checks are no longer done, so we have to be careful and get ready for anything.

Homepage